CMRG Articles
Sugar-sweetened drinks raise risk of diabetes, metabolic syndrome
Research review finds link between soda, juice consumption and health problems Washington, DC - Regularly drinking sugar-sweetened beverages such as soda and juice contributes to the development of diabetes, high blood pressure and other endemic health problems, accordi
Here’s how stress can cause diabetes
Researchers established that people who suffer from work strain and/or emotional stress are more likely to develop diabetes than those with relatively lower stress levels. The growing burden of diabetes represents a global health challenge with considerable consequences
Trimetazidine therapy for diabetic mouse hearts subjected to ex vivo acute heart failure
[et_pb_row] Cardiovascular diseases (CVD) remain the leading cause of global mortality accounting for ~30% of all deaths worldwide [1, 2]. Future projections also indicate that both developed and developing nations face a growing CVD burden, e.g. heart failure prevalenc
The Transcription Profile Unveils the Cardio-Protective Effect of Aspalathin against Lipid Toxicity in an In Vitro H9c2 Model
[et_pb_row] During the last decade, there has been considerable interest in the use of plant-derived polyphenols as nutraceuticals to slow down the progression of metabolic diseases [1,2]. Aspalathus linearis (commonly known as rooibos) is a rich source of plant polyphe
Resveratrol Co-Treatment Attenuates the Effects of HIV Protease Inhibitors on Rat Body Weight and Enhances Cardiac Mitochondrial Respiration
[et_pb_row] The human immunodeficiency virus (HIV) has become a global pandemic over the last 30 years, affecting ~34 million people (2010), of which 2.7 million were children under the age of 15 years old [1]. Although it began as a relatively insignificant disease dur
Phenylpyruvic Acid-2-O-β-D-Glucoside Attenuates High Glucose-Induced Apoptosis in H9c2 Cardiomyocytes
[et_pb_row] Chronic hyperglycemia is closely associated with impaired substrate metabolism, dysregulated mitochondrial membrane potential, and apopto-sis in the diabetic heart. As adult cardiomyocytes display a limited capacity to regenerate following an insult, it is e
Health Benefits of Fasting and Caloric Restriction
[et_pb_row] It is abundantly clear that the obesity epidemic has affected most countries in the Middle East more severely [1, 2, 3•, 4, 5]. It is disconcerting that increases in the rates of obesity and type 2 diabetes continue unabated in spite of great efforts at soun
Glycation abolishes the cardioprotective effects of albumin during ex vivo ischemia-reperfusion
[et_pb_row] Cardiovascular diseases (CVD) due to hyperglycemia are a leading cause of mortality (Mulnier et al. 2006). This poses a significant health burden as the global prevalence of diabetes is surging (Mbanya et al. 2010). There is a growing interest to better under
Enhanced oxidative stress in adipose tissue from diabetic mice, possible contribution of glycated albumin
[et_pb_row] Introduction Oxidative stress is defined as “an imbalance between oxidants and anti-oxidants in favor of the oxidants, leading to a disruption of redox signaling and control and/or molecular damage” [1]. While reactive oxygen species (ROS) can act as signalin
Diabetes-induced hepatic oxidative stress: a new pathogenic role for glycated albumin
[et_pb_row] Diabetes mellitus is an endocrine metabolic disease of increasing incidence and is associated with serious complications contributing to high morbidity and mortality rates [1]. Several metabolic and signaling pathways become dysfunctional and contribute to c